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A truck collided with the sedan on Route 206 near Oakwood Drive South around 7 a.m., a press release said.
The woman was rushed to a nearby hospital for treatment of serious injuries, according to the release.
Initial reports said a medical helicopter was called to the scene for transport.
The area was temporarily shut down during the crash investigation and cleanup, police said.
The accident remained under investigation by the Mount Olive Police Department. No further details were released.
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